SR9009 (STENABOLIC)
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What Is SR9009 (STENABOLIC)?
SR9009, or Stenabolic, is a synthetic REV-ERB agonist that modulates the body's circadian rhythm by binding to REV-ERBα and REV-ERBβ nuclear receptors. It is primarily used to enhance metabolic activity, increase mitochondrial count in skeletal muscle, and improve exercise endurance and weight loss.
SR9009 (STENABOLIC) Research & Studies
01 SR9009 has REV-ERB-independent effects on cell proliferation and metabolism ▸
This study reveals that while SR9009 is a REV-ERB agonist, it also exerts significant effects on cellular metabolism and gene transcription independent of these receptors.
View Study (PubMed)02 In vitro metabolic studies of REV-ERB agonists SR9009 and SR9011 ▸
Researchers identified eight primary metabolites of SR9009 to help improve detection and screening methods for this performance-enhancing compound.
View Study (PubMed)SR9009 (STENABOLIC) User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users are often intrigued by the metabolic and endurance benefits but frequently express concerns regarding its extremely low oral bioavailability and lack of human safety data.
SR9009 (STENABOLIC) Benefits, Dosage & Side Effects
- Endurance Enhancement: Users report a significant increase in cardiovascular stamina and the ability to train longer without fatigue.
- Metabolic Boost: Reported to increase basal metabolic rate, assisting in fat loss even during sedentary periods.
- Circadian Regulation: Some users note it helps reset sleep-wake cycles, leading to higher morning alertness.
- Wakefulness: Often described as providing a clean, non-jittery energy boost similar to a high-end endurance supplement.
- Bioavailability Issues: A major concern is its poor oral absorption; many users find oral capsules ineffective compared to injectable or sublingual forms.
- Short Half-Life: The compound has a very short window of activity, requiring multiple daily doses to maintain stable levels in the blood.
- Rapid Action: Users who respond well typically report feeling the endurance-enhancing effects within the first week of use.
- Non-Hormonal: Unlike SARMs, it does not suppress natural testosterone, making it popular for those looking to avoid hormonal side effects.
- Standard Protocol: A common research dose mentioned is 20-30mg total per day, divided into 3-4 smaller doses.
- Frequency: Due to a 4-hour half-life, users typically dose every 4-5 hours to maintain metabolic effects.
- Starting Dose: New users often start at 5mg four times a day to assess tolerance before increasing the amount.
- Administration Method: Sublingual dosing is frequently recommended by the community to bypass first-pass metabolism in the liver.
- Insomnia: Because it modulates circadian rhythms, taking it too late in the evening can disrupt sleep patterns.
- Nausea: Some users report digestive upset or a 'chemical' taste when using liquid or sublingual versions.
- Unknown Long-term Profile: As a research chemical with no human clinical trials, long-term safety and organ toxicity remain unquantified.
- Lethargy Post-Cycle: A small number of users report a 'crash' in energy levels once the compound is discontinued.
- Research Chemical Status: It is not FDA-approved for human consumption and is sold primarily for 'laboratory research' purposes.
- Doping Control: It is explicitly banned by WADA and most professional sporting organizations under the category of metabolic modulators.
- Black Market Quality: Studies have found that products sold online as SR9009 often contain varying purity levels or different substances entirely.
Related Compounds
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