Pramiracetam
What Is Pramiracetam?
Pramiracetam is one of the most potent racetams, approximately 15-30x stronger than piracetam. It's particularly noted for enhancing long-term memory formation and high-affinity choline uptake, making it popular for learning and studying.
Pramiracetam Research & Studies
01 Pramiracetam effects on scopolamine-induced amnesia in healthy volunteers ▸
Study examined pramiracetam's ability to counteract memory loss induced by scopolamine in healthy male volunteers, showing pramiracetam partly reduced amnesic effects compared to placebo.
View Study (PubMed)02 Pharmacokinetics of oral pramiracetam in normal volunteers ▸
Study assessed pramiracetam's pharmacokinetics in healthy male volunteers receiving varying doses, demonstrating predictable absorption and clearance rates without significant side effects.
View Study (PubMed)03 Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia ▸
Found that 400 mg pramiracetam sulphate taken three times daily significantly improved memory, particularly delayed recall, in males with brain injuries versus placebo.
View Study (PubMed)04 A new one-trial test for neurobiological studies of memory in rats. Effects of piracetam and pramiracetam ▸
Study assessed nootropic effects on rats' recognition memory using exploratory behavior tests. Specific pramiracetam doses significantly improved object recognition after 24 hours.
View Study (ScienceDirect)05 Some neurochemical properties of pramiracetam (CI-879), a new cognition-enhancing agent ▸
Investigated pramiracetam's neurochemical effects and found it significantly increased choline uptake in the hippocampus, suggesting cognitive enhancement through boosted acetylcholine turnover.
View Study (Warner-Lambert Pharmaceutical Research)Pramiracetam User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Highly regarded for memory enhancement and studying. Users report significant improvements in recall and learning. Less emotional effect than aniracetam.
Pramiracetam Benefits, Dosage & Side Effects
- Memory Enhancement: Strong effects on long-term memory.
- Focus: Improved concentration without stimulation.
- Learning: Enhanced ability to acquire and retain information.
- Minimal Mood Effects: Pure cognitive enhancement without mood changes.
- Choline Utilization: Significantly increases choline uptake.
- Highly Potent: Effective at much lower doses than piracetam.
- Consistent: Reliable cognitive enhancement for most users.
- Choline Demanding: Requires adequate choline more than other racetams.
- Typical Range: 250-400mg twice daily.
- With Fats: Fat-soluble; best absorbed with dietary fat.
- Choline Essential: Must supplement choline to avoid headaches.
- Headaches: Very common without choline supplementation.
- Emotional Blunting: Some report reduced emotional intensity.
- GI Upset: Possible with high doses.
- Generally Well Tolerated: Safe at recommended doses.
- Research Chemical: Available from nootropic suppliers.
- Prescription in Europe: Available by prescription in some countries.
- Higher Cost: More expensive than piracetam due to potency.
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