NIGELLA SATIVA
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What Is NIGELLA SATIVA?
Nigella sativa, commonly known as black cumin or black seed, is a medicinal herb containing the potent bioactive compound thymoquinone, which exerts anti-inflammatory, antioxidant, and immunomodulatory effects. It is primarily used as a dietary supplement to support immune health, manage metabolic disorders like diabetes, and reduce chronic inflammation.
NIGELLA SATIVA Research & Studies
01 Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety ▸
A broad review detailing the plant's therapeutic potential against chronic illnesses including cardiovascular disorders, diabetes, and inflammatory conditions via its rich bioactive profile.
View Study (PubMed)02 Black Seed (Nigella sativa): A Favourable Alternative Therapy for Inflammatory and Immune System Disorders ▸
This review confirms that black seed modulates key inflammatory mediators like TNF-α and NF-kB, making it a viable therapy for immune-dysregulation and inflammatory disorders.
View Study (PubMed)03 Nigella sativa: A Dietary Supplement as an Immune-Modulator on the Basis of Bioactive Components ▸
A systematic study identifying new bioactive compounds in the seeds that contribute specifically to its antibacterial and immune-regulating properties.
View Study (PubMed)04 Comparative effects of nutraceuticals on body weight in adults with overweight or obesity: A systematic review and network meta-analysis ▸
A meta-analysis of 111 trials ranking Nigella sativa among effective nutraceuticals for weight loss and body mass index reduction in adults.
View Study (PubMed)05 Effect of Nigella sativa oil supplement on risk factors for cardiovascular diseases in patients with type 2 diabetes mellitus ▸
Clinical evidence showing that black seed oil supplementation improves glycemic control and reduces cardiovascular risk factors in diabetic patients.
View Study (PubMed)NIGELLA SATIVA User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users widely report significant benefits for mood stabilization, anxiety reduction, and seasonal allergy relief, with many considering it a staple for general well-being.
NIGELLA SATIVA Benefits, Dosage & Side Effects
- Mood Elevation: Users frequently report a noticeable 'mood boost' and reduction in symptoms of depression or general anxiety.
- Anti-Inflammatory: Both clinical and anecdotal evidence highlight its ability to reduce systemic inflammation and help with recovery from illness.
- Immune Support: Highly regarded as a prophylactic or recovery aid for respiratory viruses, including viral load reduction.
- Allergy Relief: Users report significant reduction in hay fever and allergic rhinitis symptoms when taken consistently.
- Clinical Consistency: Metanalyses confirm its efficacy for weight loss, glycemic control in diabetics, and asthma management.
- Viral Clearance: Research suggests it may expedite the clearance of viral infections when paired with honey or taken as an oil.
- Weight Management: Ranked as one of the more effective natural supplements for reducing BMI in overweight populations.
- Nootropic Potential: Some users find it effective for focus and managing mild ADHD symptoms when stacked with other adaptogens.
- Standard Capsule Dose: Commonly taken as 500mg capsules, often three times daily for general health.
- Liquid Oil Protocol: Users suggest starting with 1/2 teaspoon twice daily, gradually increasing to a full tablespoon.
- Therapeutic Window: Most research focuses on doses between 1-3 grams of powder or 2-5ml of oil daily.
- Stacking Timing: Often taken in the afternoon (3-4 PM) to bridge the gap between morning energy boosters and evening relaxation aids.
- Digestive Upset: Some users report 'black seed burps' or mild stomach discomfort when taking the liquid oil form.
- Contact Dermatitis: Topical application of the oil can cause allergic skin reactions in sensitive individuals.
- Blood Thinning: Due to its effects on circulation, it may have mild anti-coagulant properties that require caution before surgery.
- Drug Interactions: May inhibit CYP3A4 enzymes, potentially slowing the metabolism of certain medications like benzodiazepines.
- Legal Status: Widely available as an over-the-counter dietary supplement in oil, capsule, and raw seed form.
- Quality Variation: Users emphasize the importance of high-quality 'cold-pressed' oils to ensure thymoquinone content is preserved.
- Global Tradition: Primarily sourced from Egypt, Turkey, and India, where it has deep historical use in traditional medicine.
Related Compounds
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