N-ACETYL SELANK
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What Is N-ACETYL SELANK?
N-Acetylcysteine (NAC) is a derivative of the amino acid L-cysteine that serves as a precursor to glutathione, the body's primary antioxidant. It works by replenishing glutathione levels, supporting liver detoxification, reducing oxidative stress, and modulating glutamate neurotransmission. NAC is FDA-approved as a medication for acetaminophen overdose and is commonly used as a supplement for respiratory health, mental health conditions, and overall antioxidant support.
N-ACETYL SELANK Research & Studies
01 N-Acetylcysteine Ineffective in Alleviating Hangover from Binge Drinking: A Clinical Study ▸
A clinical trial found that NAC did not significantly reduce hangover symptoms from binge drinking, challenging its popular use for alcohol-related recovery.
View Study (PubMed)02 The use of N-acetylcysteine in the prevention of hangover: a randomized trial ▸
A randomized controlled trial tested NAC for hangover prevention, finding limited effectiveness in reducing alcohol-induced symptoms.
View Study (PubMed)03 N acetylcysteine in the treatment of alcohol use disorder: a randomized, double-blind, placebo-controlled trial ▸
A double-blind RCT examined NAC's efficacy in treating alcohol use disorder, with results showing potential benefits for reducing alcohol consumption and cravings.
View Study (PubMed)N-ACETYL SELANK User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users report NAC as highly effective for anxiety, OCD, compulsive behaviors, autoimmune conditions, and respiratory health. While some experience no noticeable effects and a few report negative reactions like insomnia or brain fog, the majority find it beneficial for mental health, inflammation reduction, and immune support, with many taking it long-term without issues.
N-ACETYL SELANK Benefits, Dosage & Side Effects
- Anxiety & OCD Relief: Users consistently report significant reductions in anxiety, intrusive thoughts, and compulsive behaviors like skin picking
- Autoimmune Support: Multiple users with autoimmune diseases report reduced inflammation and symptom improvement when combined with lifestyle changes
- Respiratory & Immune Health: Frequently mentioned as helpful for lung health, respiratory infections, and immune system support, particularly during illness
- Mental Clarity: Some users report improved focus and reduced brain fog, though effects vary and may take weeks to manifest
- Onset Time: Effects typically appear within 2 hours to 2 weeks, with mental health benefits often taking longer to fully manifest
- Consistency: Works well for some users with no tolerance buildup over years of use, while others report no noticeable effects even after extended trials
- Synergy: Often more effective when combined with glycine (as GlyNAC) for glutathione synthesis, sleep quality, and recovery benefits
- Individual Response: Highly variable effectiveness, with genetic factors and specific conditions influencing outcomes significantly
- Standard Dose: 600mg once or twice daily is the most commonly reported dosage, typically taken in the morning or split throughout the day
- Therapeutic Range: Higher doses of 1000-1800mg daily are used for specific conditions like autoimmune disease, OCD, or intensive recovery protocols
- Timing: Often taken with food to reduce potential stomach upset, though some take it on an empty stomach for better absorption
- Cycling: Most users take it daily long-term without cycling, though some recommend occasional breaks to assess continued need
- Gastrointestinal Issues: Nausea and stomach discomfort are the most commonly reported side effects, especially at higher doses or on empty stomach
- Sleep Disruption: Some users report insomnia, restlessness, or overstimulation when taken too late in the day or at high doses
- Rare Negative Reactions: A small subset reports brain fog, headaches, or worsening anxiety, though these are uncommon and may indicate dosing issues
- Generally Well-Tolerated: Most users report no side effects with standard dosing, and long-term use appears safe for the majority
- FDA Controversy: NAC was approved as a drug in 1963, leading to FDA attempts to remove it from the supplement market, though it remains widely available
- Common Sources: Available from major supplement retailers, though online platforms have restricted sales due to regulatory concerns
- Cost: Relatively inexpensive supplement, with bulk powder forms offering significantly better value than capsules
Related Compounds
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