MARSHMALLOW ROOT
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What Is MARSHMALLOW ROOT?
Marshmallow root (Althaea officinalis L.) is a medicinal plant containing mucilaginous polysaccharides that form a protective film on mucous membranes. The root extract has demonstrated anti-inflammatory, anti-oxidative, and cytoprotective effects on epithelial cells and macrophages in laboratory studies. Traditionally used for centuries to treat respiratory irritation, cough, and mild gastrointestinal discomfort.
MARSHMALLOW ROOT Research & Studies
01 Anti-inflammatory and Anti-oxidative Effects of Phytohustil and Root Extract of Althaea officinalis L. on Macrophages in vitro ▸
Marshmallow root extract protected human macrophages against oxidative stress, reduced inflammatory cytokines (IL-6, IL-8, TNF-α), and decreased ROS production while maintaining cell viability and migratory capacity.
View Study (PubMed)02 Aqueous extracts and polysaccharides from Marshmallow roots: Cellular internalisation and stimulation of cell physiology of human epithelial cells in vitro ▸
Marshmallow root polysaccharides stimulated epithelial cell viability and were internalized into cells, while forming bioadhesive layers on fibroblasts, with gene expression analysis showing up-regulation of cell adhesion proteins and growth regulators.
View Study (PubMed)03 Phytochemical Characterization of Low Molecular Weight Constituents from Marshmallow Roots and Inhibiting Effects of the Aqueous Extract on Human Hyaluronidase-1 ▸
Marshmallow root aqueous extract demonstrated inhibitory effects on human hyaluronidase-1 enzyme, which may contribute to its anti-inflammatory properties and mucous membrane protective effects.
View Study (PubMed)MARSHMALLOW ROOT User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Marshmallow root receives limited direct discussion in user communities, with most mentions appearing in broader herbal remedy contexts. Users seeking natural anti-inflammatory and gut health solutions show interest, but specific experiential reports are scarce compared to other supplements.
MARSHMALLOW ROOT Benefits, Dosage & Side Effects
- Mucous Membrane Protection: Forms protective film on irritated throat and oral tissues reducing discomfort
- Anti-inflammatory Action: Reduces inflammatory markers in respiratory and digestive tract tissues
- Gut Comfort: Provides mild relief from gastrointestinal discomfort through mucilage coating
- Antioxidant Support: Protects cells against oxidative stress and ROS production
- Immediate Relief: Provides quick soothing effect on irritated mucous membranes upon contact
- Synergistic Benefits: Often works better in combination with other herbal remedies for respiratory and digestive issues
- Traditional Validation: Long-standing use supported by modern in vitro research showing cellular mechanisms
- Targeted Action: Most effective for localized irritation rather than systemic inflammation
- Tea Preparation: Commonly used as herbal tea for throat irritation and cough relief
- Age Restrictions: Suitable for adults, adolescents and children over 3 years for respiratory issues; adults and adolescents over 12 for digestive complaints
- Duration: Recommended for short-term use (1 week maximum) unless symptoms persist
- Extract Forms: Available as dry extracts, liquid extracts, syrups, and raw polysaccharide preparations
- Minimal Toxicity: Generally well-tolerated with few reported adverse effects in clinical use
- Ethanol Considerations: Alcohol-based extracts restricted to adults only due to ethanol content
- Drug Interactions: Mucilage may affect absorption of other medications when taken simultaneously
- Allergic Reactions: Rare cases of allergic response in individuals sensitive to Malvaceae family plants
- Wide Availability: Commonly found in herbal tea blends, throat lozenges, and cough syrups
- Regulatory Status: Recognized by European Medicines Agency for traditional herbal medicinal use
- Combination Products: Frequently combined with other respiratory herbs in commercial formulations
Related Compounds
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