GUARANA
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What Is GUARANA?
Guarana (Paullinia cupana) is an Amazonian plant rich in methylxanthines, particularly caffeine, and polyphenols like catechins and epicatechins. It functions as a central nervous system stimulant and antioxidant, widely used to enhance cognitive performance, reduce fatigue, and support metabolic health.
GUARANA Research & Studies
01 Effects of the consumption of guarana on human health: A narrative review ▸
A comprehensive review highlighting guarana's stimulating, anti-inflammatory, and anti-obesity effects driven by its high content of methylxanthines and flavonoids.
View Study (PubMed)02 Cognitive effects of guarana supplementation with maximal intensity cycling ▸
Research demonstrating that guarana significantly improves reaction times and cognitive performance both before and after high-intensity physical exercise.
View Study (PubMed)03 Guarana provides additional stimulation over caffeine alone in the planarian model ▸
Laboratory evidence suggesting that the complex phytochemistry of guarana seeds produces a stronger stimulant effect than anhydrous caffeine alone.
View Study (PubMed)04 The use of guarana (Paullinia cupana) as a dietary supplement for fatigue in cancer patients ▸
A systematic review and meta-analysis evaluating guarana's effectiveness in managing physiological fatigue in clinical populations.
View Study (PubMed)05 Effects of Guarana and Green Tea Consumption on Students' Intellectual Performances ▸
A 2025 study found that daily guarana consumption improved reaction speed, memory, and attention scores in university students.
View Study (PubMed)GUARANA User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users overwhelmingly prefer guarana over coffee for its 'smoother' energy delivery and lack of a harsh 'crash,' noting it provides sustained alertness for hours.
GUARANA Benefits, Dosage & Side Effects
- Sustained Alertness: Users report a prolonged state of wakefulness without the typical jitteriness associated with high doses of coffee.
- Cognitive Sharpness: Improved mental clarity and the ability to find words or process information faster during demanding tasks.
- Mood Elevation: A subtle brightening of mood often described as a 'clean' sense of well-being alongside the stimulation.
- Physical Synergies: Highly effective when taken before exercise to maintain cognitive focus under physical strain.
- Comparison to Caffeine: Both research and users suggest guarana out-performs pure caffeine due to its secondary bioactive compounds.
- Fatigue Reduction: Proven effective in reducing both mental fatigue from studying and physical fatigue in clinical settings.
- Standard Powder Dose: Common supplemental doses range from 500 mg to 2000 mg of seed powder daily.
- Extract Ratios: High-potency extracts are often standardized to 10-22% caffeine, requiring much lower gram dosages.
- Incremental Dosing: Users recommend starting with small doses (200-500 mg) to assess individual sensitivity to its potent stimulant effects.
- Insomnia: Due to its long half-life, evening consumption can significantly disrupt sleep patterns.
- Tachycardia: Excess intake may lead to a rapid heart rate or palpitations in sensitive individuals.
- Digestive Issues: Some users report mild stomach upset if taken on an empty stomach without adequate hydration.
- GRAS Status: Generally Recognized As Safe (GRAS) by the FDA when used as a flavoring or dietary ingredient.
- Market Forms: Widely available as a bulk powder, encapsulated extract, or a key ingredient in 'natural' energy drinks.
Related Compounds
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