DEMOXYTOCIN
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What Is DEMOXYTOCIN?
Demoxytocin is a synthetic analog of the neuropeptide oxytocin, modified by the removal of the N-terminal amino group to increase its resistance to enzymatic degradation and extend its half-life. It primarily functions as an agonist at the oxytocin receptor, facilitating uterine contractions and milk ejection while modulating central social behaviors and stress responses.
DEMOXYTOCIN Research & Studies
01 Oxytocin ▸
This systematic review details oxytocin's essential role in lactation and its potential calming effects, while noting that exogenous administration can impact maternal-infant bonding and birth outcomes.
View Study (PubMed)02 The Peptide That Binds: A Systematic Review of Oxytocin and Social Behavior ▸
This review establishes that oxytocin administration alters social decision-making, eye contact, and social memory, framing it as a key regulator of the human social brain.
View Study (PubMed)03 The role of oxytocin in psychiatric disorders: A review of biological and therapeutic research findings ▸
The research highlights oxytocin's therapeutic potential for conditions involving social dysfunction and anxiety, specifically citing its role in pair-bonding and social attachment.
View Study (PubMed)04 Chronic oxytocin administration as a tool for investigation and treatment: A cross-disciplinary systematic review ▸
A comprehensive analysis showing that long-term oxytocin administration can improve adaptive physiological and behavioral functions across various clinical contexts.
View Study (PubMed)DEMOXYTOCIN User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users generally report significant improvements in social anxiety and emotional warmth, though some note that the 'short-lived' nature of standard oxytocin is improved by the Demoxytocin analog.
DEMOXYTOCIN Benefits, Dosage & Side Effects
- Social Bonding: Users report an increased desire for social interaction and a feeling of 'emotional warmth' or 'connectedness'.
- Anxiolytic Action: A notable reduction in social anxiety and the physiological symptoms of stress.
- Trust Enhancement: Subjective reports of increased trust and reduced suspicion in social environments.
- Calming Effect: A generalized reduction in the 'fight or flight' response, facilitating relaxation.
- Half-Life: Demoxytocin is regarded as more effective than regular oxytocin because it resists breakdown by aminopeptidases, leading to a longer duration of action.
- Social Context: Effectiveness is highly dependent on environment; it works best in social settings rather than in isolation.
- Biological Variability: Users report varied results based on baseline endogenous oxytocin levels and receptor sensitivity.
- Intranasal Administration: Most commonly used via nasal spray to bypass the blood-brain barrier effectively.
- Standard Range: Typical doses range from 10 IU to 40 IU per application depending on individual tolerance.
- Chronic vs Acute: While acute doses are used for social events, chronic low-dose administration is sometimes used for mood regulation.
- Mild Headache: Some users report pressure or mild headaches shortly after administration.
- Emotional Blunting: A small subset of users reports feeling 'too calm' or slightly detached from negative emotions.
- Uterine Contractions: As a potent agonist, it carries a risk of stimulating uterine activity, which is a concern for pregnant users.
- Prescription Status: In many regions, the analog is available via prescription for lactation or labor support, though often sourced via compounding pharmacies.
- Research Chemicals: Frequently found in the 'nootropic' and 'peptide' grey market as a research chemical.
Related Compounds
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