CAT'S CLAW
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What Is CAT'S CLAW?
Cat's Claw (Uncaria tomentosa) is a woody vine native to the Amazon rainforest known for its potent anti-inflammatory and immunomodulatory properties. Its mechanisms include the inhibition of NF-kappaB and the reduction of pro-inflammatory cytokines such as IL-6, making it a primary supplement for managing chronic inflammatory conditions and supporting immune health.
CAT'S CLAW Research & Studies
01 Anti-inflammatory and/or immunomodulatory activities of Uncaria tomentosa (cat's claw) extracts: A systematic review and meta-analysis of in vivo studies ▸
This meta-analysis confirmed that Cat's Claw significantly reduces pro-inflammatory mediators like IL-6 and NF-κB, validating its traditional use for inflammatory diseases.
View Study (PubMed)02 Uncaria tomentosa (Cat's Claw) Improves Quality of Life in Patients with Advanced Solid Tumors ▸
Research indicates that Cat's Claw supplementation significantly reduces fatigue and improves the overall quality of life and social functioning in patients with advanced cancer.
View Study (PubMed)CAT'S CLAW User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
Users generally view Cat's Claw as a powerful tool for 'dragging oneself out' of states of severe fatigue and chronic illness, frequently citing its effectiveness in complex recovery stacks.
CAT'S CLAW Benefits, Dosage & Side Effects
- Inflammation Reduction: Users and studies report a marked decrease in systemic inflammation markers and related discomfort.
- Fatigue Mitigation: Significant reports of restored energy levels in individuals suffering from chronic exhaustion or recovery from severe illness.
- Immune System Modulation: Acts to balance immune response, often used by those with autoimmune concerns or chronic viral symptoms.
- Quality of Life: Clinical evidence shows it improves social functioning and reduces the 'burden' of chronic disease symptoms.
- Synergistic Potential: Users report high effectiveness when paired with lifestyle changes like exercise and specific dietary protocols.
- Symptom Management: While not always 'curing' underlying conditions, it is highly effective at managing secondary symptoms like brain fog and lethargy.
- Standard Extract Dose: Many clinical studies utilize 100mg of dry extract taken three times daily.
- Biohacker Consensus: Users often start with lower doses to assess tolerance before moving to standard therapeutic ranges.
- Tea vs. Capsules: Traditional use favors bark tea, but supplement users prefer standardized extracts for consistent alkaloid content.
- Gastrointestinal Sensitivity: Some users with sensitive stomachs report mild digestive upset or nausea.
- Blood Pressure Interaction: Potential for hypotensive effects, requiring caution when combined with other blood-pressure-lowering agents.
- Hormonal Influence: Minimal anecdotal reports suggest monitoring mood changes during specific hormonal cycles (e.g., PMDD).
- Legal Status: Widely available as an over-the-counter dietary supplement in most countries.
- Sourcing Varieties: Critical to distinguish between Uncaria tomentosa (preferred) and Uncaria guaianensis, as their chemical profiles differ.
Related Compounds
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