BMS-564929
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What Is BMS-564929?
BMS-564929 is a potent, orally active nonsteroidal selective androgen receptor modulator (SARM) designed to treat age-related declines in muscle mass and physical function. It works by acting as a high-affinity agonist for androgen receptors in muscle and bone while maintaining significant tissue selectivity to avoid stimulating the prostate.
BMS-564929 Research & Studies
01 Ockham's Razor and Selective Androgen Receptor Modulators (SARMs): Are We Overlooking the Role of 5α-Reductase? ▸
This study explains how SARMs like BMS-564929 achieve selectivity because they are not substrates for 5α-reductase, preventing the localized amplification of androgenic effects in the prostate.
View Study (PubMed)02 Selective Androgen Receptor Modulators (SARMs) as Function Promoting Therapies ▸
Research indicates that nonsteroidal SARMs act as full agonists in muscle and bone while acting as only partial agonists in the prostate, offering a safer profile than traditional steroids.
View Study (PubMed)03 Selective androgen receptor modulators: the future of androgen therapy? ▸
Clinical analysis suggests that SARMs represent a promising class of drugs for treating muscle wasting and hypogonadism with significantly reduced side effects compared to testosterone.
View Study (PubMed)BMS-564929 User Reviews & Experiences
*Based on large scale analysis of publicly available user experiences
While clinical research is highly optimistic about its tissue selectivity, user data for this specific compound is sparse compared to more common SARMs, leading to a cautious but generally curious sentiment regarding its muscle-building potential.
BMS-564929 Benefits, Dosage & Side Effects
- Anabolic Muscle Growth: Promotes significant increases in lean body mass by binding to androgen receptors in skeletal muscle
- Prostate Sparing: Exhibits much lower androgenic activity in the prostate compared to testosterone or DHT
- Bone Mineral Density: Research indicates potential for strengthening bone structure similarly to traditional androgens
- High Potency: In preclinical models, it has shown to be more potent than testosterone in stimulating muscle growth per milligram
- Tissue Selectivity: Highly effective at separating muscle-building benefits from undesirable androgenic side effects
- Oral Bioavailability: Unlike many traditional androgens, it is designed for effective oral administration
- Clinical Trials: Doses in human research have been evaluated at very low levels (e.g., 0.1 mg to 1 mg) due to its high potency
- Preclinical Range: Animal studies utilized doses ranging from 0.03 to 3 mg/kg to determine anabolic thresholds
- Experimental Use: Users often caution that due to high binding affinity, 'less is more' to maintain selectivity
- Hormonal Suppression: Like all SARMs, it may suppress natural testosterone production at higher dosages
- Lipid Changes: Potential reduction in HDL (good) cholesterol, a common trait across the SARM class
- SHBG Reduction: Likely to cause a decrease in Sex Hormone-Binding Globulin levels during active use
- Legal Status: Currently not FDA-approved for human use and prohibited by WADA for competitive athletes
- Research Only: Primarily available through chemical supply companies for laboratory research purposes
Related Compounds
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