What is it?

PT-141 is a synthetic peptide that acts on melanocortin receptors, primarily used for treating sexual dysfunction in men and women by stimulating arousal and increasing sexual desire.


What does science research say?

Effect of bremelanotide on body weight of obese women

Summary: Bremelanotide reduced body weight and caloric intake in obese women in clinical trials, showing promise as a treatment for weight loss by targeting the MC4R receptor.

Link: Diabetes Obesity and Metabolism

Long-term safety and efficacy of bremelanotide for Hypoactive Sexual Desire Disorder

Summary: This study found that bremelanotide effectively improved sexual desire in premenopausal women with hypoactive sexual desire disorder over 52 weeks, with minimal side effects like nausea and flushing.

Link: George Washington University

Bremelanotide for the treatment of Hypoactive Sexual Desire Disorder

Summary: In clinical trials, Bremelanotide significantly increased sexual desire and reduced distress in women with sexual dysfunction, showing a favorable safety profile.

Link: MacDonald Women’s Hospital


What do user think?
Overall sentiment*

*Based on large scale analysis of publicly available user experiences, the higher it is the better overall opinions of users on efficiency, safety, availability, etc.

Category: Effective

PT-141 is effective as many users report significant improvements in sexual arousal and erectile function, though some experience notable side effects like nausea and flushing.


Main insights

Effects

  • Enhanced Sexual Arousal: Users commonly report that PT-141 significantly increases sexual desire and arousal, leading to more intense and enjoyable sexual experiences.
  • Spontaneous and Prolonged Erections: Many male users experience strong, sometimes spontaneous erections that can occur without sexual stimulation and may last for several hours or recur over a couple of days.

    Effectiveness

    • Highly Effective for Erectile Dysfunction: PT-141 is generally considered highly effective for inducing erections, with effects lasting up to 24 hours or more for some individuals.
    • Variable Response Time: The onset of effects typically occurs 4 to 8 hours after administration, and effectiveness can vary among users, with some needing higher doses to achieve desired results.

      Dosage & Administration

      • Common Dosages: Typical dosages range from 1 mg to 2 mg, administered via subcutaneous injection using an insulin needle.
      • Timing of Administration: Users often inject PT-141 several hours before anticipated sexual activity due to the delayed onset, and starting with a lower dose is advised to assess individual tolerance.

        Side Effects

        • Nausea and Flushing: The most frequently reported side effects are nausea and facial flushing shortly after injection, which can be mild to severe depending on the dose.
        • Other Side Effects: Some users experience headaches, dizziness, prolonged erections (priapism), and, in rare cases, skin darkening or hyperpigmentation, especially with repeated use or higher doses.

        Availability & Sourcing

        • Accessible Through Various Suppliers: PT-141 can be obtained from peptide suppliers, compounding pharmacies, and online vendors.
        • Importance of Reputable Sources: Users emphasize purchasing from reputable and legitimate suppliers to ensure product quality and purity, cautioning against counterfeit products and the need for proper storage and handling.

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          Disclaimer
          The information on this website is provided for educational and informational purposes only. It is not intended as medical advice, diagnosis, or treatment. The products discussed are not approved for human use unless explicitly stated. Always consult a qualified healthcare professional before using any supplements, medications, or research compounds. We do not guarantee the accuracy, completeness, or reliability of the information presented. Use at your own risk.