What is it?
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) designed to stimulate the release of growth hormone (GH) and insulin-like growth factor I (IGF-I) with a prolonged duration of action. This peptide has garnered attention for its potential therapeutic applications and its use in performance enhancement.
What does science research say?
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.
Summary: CJC-1295, a long-acting growth hormone-releasing hormone analog, effectively increases growth hormone and IGF-I levels in healthy adults, with potential therapeutic utility.
Link: Oxford Academic
An immuno polymerase chain reaction screen for the detection of CJC-1295 and other growth-hormone-releasing hormone analogs in equine plasma.
Summary: This I-PCR assay effectively detects CJC-1295-protein conjugate in equine plasma, effectively controlling its illicit use in thoroughbred race horses.
Link: Wiley Analytical Science
Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation.
Summary: CJC-1295, a growth hormone-releasing peptide, was identified in an unknown pharmaceutical preparation, suggesting it may be used within the bodybuilding community.
Link: Wiley Analytical Science
Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.
Summary: Once-daily administration of CJC-1295 maintains normal body composition and growth in GHRH knockout mice, with less effectiveness when administered every 48 or 72 hours.
A method for confirming CJC-1295 abuse in equine plasma samples by LC-MS/MS.
Summary: This study demonstrates a method for detecting CJC-1295 abuse in equine plasma samples using LC-MS/MS, enabling detection down to low concentrations in 1 mL of plasma.
Link: Wiley Analytical Science
Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog.
Summary: CJC-1295 is a stable and active human growth hormone-releasing factor analog with an extended plasma half-life, enhancing growth hormone secretion in rats.
Link: Oxford Academic
Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog.
Summary: CJC-1295 increases growth hormone secretion and IGF-I production with preserved pulsatility, suggesting potential clinical utility for patients with intact pituitary growth hormone secretory capability.
Link: Oxford Academic
Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions
Summary: Females self-medicate with synthetic growth hormone CJC-1295 for weight loss, muscle enhancement, youthful skin, improved sleep, and injury healing, but public health interventions should consider potential adverse health consequences.
Advances in the Detection of Growth Hormone Releasing Hormone Synthetic Analogs.
Summary: This study developed a sensitive liquid chromatography-tandem mass spectrometry method for detecting growth hormone releasing hormone synthetic analogs in fortified urine, helping prove their administration.
Link: Wiley Analytical Science
What do user think?
*Based on large scale analysis of publicly available user experiences, the higher it is the better overall opinions of users on efficiency, safety, availability, etc.
Category: Mostly Effective
Users generally find it boosts growth hormone levels, with some questioning its necessity or benefit in younger users.
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